OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS (Ezine Ready)

Chlorinated aliphatic hydrocarbons, ketones, alcohols, ethers, esters, aromatics, petrol, spirit, nitrocellulose varnishes and certain plasticisers cause PMMA to swell or produce stress cracks.  The resistance to weathering of PMMA is very good. Natural colour PMMA is crystal clear and has a high surface gloss. It can be produced in all colours, transparent and muted. Health and Safety PMMA is odorless and tasteless and physiologically safe. USES PMMA or Acrylic is a versatile material and has been used in a wide range of fields and applications. Medical technologies and implants PMMA has a good degree of compatibility with human tissue, and can be used for replacement intraocular lenses in the eye when the original lens has been removed in the treatment of cataracts. Historically, hard contact lenses were frequently made of this material. Soft contact lenses are often made of a related polymer, where acrylate monomers containing one or more hydroxyl groups make them hydrophilic. In orthopedics, PMMA bone cement is used to affix implants and to remodel lost bone. It is supplied as a powder with liquid methyl methacrylate (MMA). Although PMMA is biologically compatible, MMA is considered to be an irritant and a possible carcinogen. PMMA has also been linked to cardiopulmonary events in the operating room due to hypotension. Bone cement acts like a grout and not so much like a glue in arthroplasty. Although sticky, it does not bond to either the bone or the implant, it primarily fills the spaces between the prosthesis and the bone preventing motion. Dentures are often made of PMMA, and can be colour-matched to the patient's teeth & gum tissue.

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News OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMSAuthor: Kamal Singh RathoreOPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS Kamal Singh Rathore1, S.S.Sisodia2, M.S.Ranawat2, R.K.Nema3 1B.N. Girls College of Pharmacy, Udaipur 2B.N. College of Pharmacy, Udaipur 3Rishiraj College of Pharmacy, Indore-MP INTRODUCTION Nanoparticles are defined as particulate dispersions or solid particles with a size in the range of 10-1000nm. The drug is dissolved, entrapped, encapsulated or attached to a nanoparticle matrix. Depending upon the method of preparation, nanoparticles, nanospheres or nanocapsules can be obtained.