OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS
OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMSAuthor: Kamal Singh RathoreOPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS Kamal Singh Rathore1, S.S.Sisodia2, M.S.Ranawat2, R.K.Nema3 1B.N. Girls College of Pharmacy, Udaipur 2B.N. College of Pharmacy, Udaipur 3Rishiraj College of Pharmacy, Indore-MP INTRODUCTION Nanoparticles are defined as particulate dispersions or solid particles with a size in the range of 10-1000nm. The drug is dissolved, entrapped, encapsulated or attached to a nanoparticle matrix. Depending upon the method of preparation, nanoparticles, nanospheres or nanocapsules can be obtained. The major goals in designing nanoparticles as a delivery system are to control particle size, surface properties and release of pharmacologically active agents in order to achieve the site-specific action of the drug at the therapeutically optimal rate and dose regimen. Though liposomes have been used as potential carriers with unique advantages including protecting drugs from degradation, targeting to site of action and reduction toxicity or side effects, their applications are limited due to inherent problems such as low encapsulation efficiency, rapid leakage of water-soluble drug in the presence of blood components and poor storage stability. On the other hand, polymeric nanoparticles offer some specific advantages over liposomes. For instance, they help to increase the stability of drugs/proteins and possess useful controlled release properties.
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03.12.2009
5 Essential Medical Machines Used in Hospitals5 Essential Medical Machines Used in HospitalsAuthor: Ryan FrankToday, medical equipment technology is advancing at increasingly rapid speeds, in large part because of the advent of computer technology just a few decades ago. But despite this, some of the most common and essential pieces of medical machinery still in use today had their origin in pre-computer times. Here are 5 of the top medical machines used in hospitals. DefibrillatorsDefibrillators remain the best tools for reviving patients during cardiac arrests. Defibrillators can be found in almost every hospital room today along with the first aid kit. Experiments with defibrillation started in the late 19th century, but it wasn’t until 1947 that a defibrillator was first used to resuscitate a human being: a 14 year old patient of Doctor Claude Beck. |
Top Ten Reasons to HomeschoolTop Ten Reasons to HomeschoolAuthor: Julie ClarkAs I approach this topic, I realize how ridiculous it is to assume that I can write about "THE" Top 10 reasons to homeschool. One of the main reasons to homeschool your children is that you can be at the helm. You can do it for whatever reason you want in whatever way you want, so for me to assume that I could come up with the definitive top ten reasons seems kind of silly. My top 10 reasons are top ten for me. There are many homeschooling families I know whose reasons are vastly different from mine. |