OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS (Ezine Ready)
You have permission to publish this article electronically or in print, free of charge, as long as you leave the article title, author name, body and resource box in tact (means NO changes) with the links made active and you agree to our posted . Use the tools below to copy the article in plain text form, or you can copy it as HTML, ready to copy and paste directly into a web page. HTML Version: OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS Author: Kamal Singh Rathore OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS Kamal Singh Rathore1, S.S.Sisodia2, M.S.Ranawat2, R.K.Nema3 1B.N. Girls College of Pharmacy, Udaipur 2B.N. College of Pharmacy, Udaipur 3Rishiraj College of Pharmacy, Indore-MP INTRODUCTION Nanoparticles are defined as particulate dispersions or solid particles with a size in the range of 10-1000nm. The drug is dissolved, entrapped, encapsulated or attached to a nanoparticle matrix. Depending upon the method of preparation, nanoparticles, nanospheres or nanocapsules can be obtained. The major goals in designing nanoparticles as a delivery system are to control particle size, surface properties and release of pharmacologically active agents in order to achieve the site-specific action of the drug at the therapeutically optimal rate and dose regimen. Though liposomes have been used as potential carriers with unique advantages including protecting drugs from degradation, targeting to site of action and reduction toxicity or side effects, their applications are limited due to inherent problems such as low encapsulation efficiency, rapid leakage of water-soluble drug in the presence of blood components and poor storage stability.
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01.02.2010
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