OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS (Ezine Ready)
The selection of matrix materials is dependent on many factors Including, Size of nanoparticles required. Inherent properties of the drug, e.g., aqueous solubility and stability. Surface characteristics such as charge and permeability. Degree of biodegradability, biocompatibility and toxicity. Drug release profile desired. Antigenicity of the final product. Methods: Dispersion of preformed polymers Solvent evaporation method Spontaneous emulsification or solvent diffusion Method Polymerization method Coacervation or ionic gelation method Production of nanoparticles using supercritical fluid POLY METHYL METHACRYLATE (PMMA) (ACRYLIC) Structure of Polymethyl Methacrylate Molecular formula (C5O2H8)n INTRODUCTION Poly (methyl methacrylate) (PMMA) poly (methyl 2-methylpropenoate) is a thermoplastic and transparent plastic. Chemically, it is the synthetic polymer of methyl methacrylate. PMMA is often used as an alternative to glass, and in competition with polycarbonate (PC). It is often preferred because of its moderate properties, easy handling and processing, and low cost, but behaves in a brittle manner when loaded, especially under an impact force. Acrylic, or acrylic fiber, canalso refer to polymers or copolymers containing polyacrylonitrile. The material was developed in 1928 in various laboratories and was brought to market in 1933 by Rohm and Haas Company. Trade names: Plexiglas, Vitroflex, Limacryl, R-Cast, Per-Clax, Perspex, Plazcryl, Acrylex, Acrylite, Acrylplast, Altuglas, Polycast, Oroglass and Lucite and is commonly called acrylic glass, simply acrylic or plexiglas.Pages: 1 2 3 4 5 6 7 8 9 [10] 11 12 13 14
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01.02.2010
Does the Internet Benefit Small Travel Businesses?Does the Internet Benefit Small Travel Businesses?Author: Anthony FrancisYes, of course it does, but as much as it should? When you think of the number of travel directories and websites available to travelers you would think that this is a world free of the normal conventions of business but unfortunately it is often bound by restrictions that travelers would not appreciate. Pricing of travel is one of the conventions that are not yet totally free of restrictions and understandably so due to distribution considerations. Travel businesses using the traditional distribution chains for the sale of their products need to allow for the payments of commission to various levels of middlemen, Inbound Tour Operators, Wholesalers and Retailers, all who need to take a percentage for their efforts in enabling travel services and products to reach the consumer. |
Cutting-Edge Methods Help Target Call Center WasteCutting-Edge Methods Help Target Call Center WasteAuthor: Tony JacowskiAncillary call center processes have been perfect opportunities to implement Lean Six Sigma. However, some additional effort is needed on the main process of the call center - the call handling process. With some software systems it is possible to bring about Lean culture and the elimination of waste. Waste in Call Center Scenario The agents in call centers will have to be considered as the processes, as they are ones who deal with customer calls. There will typically be a few types of calls received at the call center, but they may be responded to differently each time, as the person on the other end may react differently. |