OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS (Ezine Ready)
In addition, small particles size and large surface area readily result in limited drug loading and burst release. These practical problems have to be overcome before nanoparticles can be used clinically or made commercially available. The present review details the latest development of nanoparticulate drug delivery systems, surface modification issues, drug loading strategies, release control and potential applications of nanoparticles. Preparation of nanoparticles Methods: Nanoparticles can be prepared from a variety of materials such as proteins, polysaccharides and synthetic polymers. The selection of matrix materials is dependent on many factors Including, Size of nanoparticles required.Inherent properties of the drug, e.g., aqueous solubility and stability.Surface characteristics such as charge and permeability.Degree of biodegradability, biocompatibility and toxicity. Drug release profile desired.Antigenicity of the final product.Methods: Dispersion of preformed polymersSolvent evaporation methodSpontaneous emulsification or solvent diffusion MethodPolymerization methodCoacervation or ionic gelation methodProduction of nanoparticles using supercritical fluid POLY METHYL METHACRYLATE (PMMA) (ACRYLIC) Structure of Polymethyl MethacrylateMolecular formula (C5O2H8)nINTRODUCTIONPoly (methyl methacrylate) (PMMA) poly (methyl 2-methylpropenoate) is a thermoplastic and transparent plastic. Chemically, it is the synthetic polymer of methyl methacrylate. PMMA is often used as an alternative to glass, and in competition with polycarbonate (PC).Pages: 1 2 [3] 4 5 6 7 8 9 10 11 12 13 14
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01.02.2010
Higher Education OnlineHigher Education OnlineAuthor: Mark WoodcockThe traditional method of attending an institution of higher learning was to go to a school and attend classes inside a building, sitting at a desk, and listening to an instructor face-to-face. Today, because of the benefits of technology and the Internet, it is possible to attain a higher education online. Not only can a student receive a bachelor's degree online, but it is also possible to earn a master's degree, and even a PhD via the Internet. Traditional colleges and universities are taking part in an educational and technological revolution in joining with online-only institutions to offer bachelor's degrees, master's degrees, and PhD degrees to students from every corner of the planet. |
General Auto Insurance and Some of the Basic Information You Should KnowGeneral Auto Insurance and Some of the Basic Information You Should KnowAuthor: Christopher CooneyToday it is a privilege for you to drive, but there is a price tag to having this privilege. Of course one of the things you are required to have by law if you are driving is general auto insurance. The insurance rate that you pay is the premium that you have to pay to a company that provides insurance for the coverage that you need. The insurance coverage helps to protect you from financial losses that can occur because of an accident, and without the coverage you would be responsible to pay for.Of course general auto insurance is far more than just a way to insure your car to pay for repairs if an accident occurs. |