OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS
OPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMSAuthor: Kamal Singh RathoreOPHTHALMIC NANOPARTICLES DRUG DELIVERY SYSTEMS Kamal Singh Rathore1, S.S.Sisodia2, M.S.Ranawat2, R.K.Nema3 1B.N. Girls College of Pharmacy, Udaipur 2B.N. College of Pharmacy, Udaipur 3Rishiraj College of Pharmacy, Indore-MP INTRODUCTION Nanoparticles are defined as particulate dispersions or solid particles with a size in the range of 10-1000nm. The drug is dissolved, entrapped, encapsulated or attached to a nanoparticle matrix. Depending upon the method of preparation, nanoparticles, nanospheres or nanocapsules can be obtained. The major goals in designing nanoparticles as a delivery system are to control particle size, surface properties and release of pharmacologically active agents in order to achieve the site-specific action of the drug at the therapeutically optimal rate and dose regimen. Though liposomes have been used as potential carriers with unique advantages including protecting drugs from degradation, targeting to site of action and reduction toxicity or side effects, their applications are limited due to inherent problems such as low encapsulation efficiency, rapid leakage of water-soluble drug in the presence of blood components and poor storage stability. On the other hand, polymeric nanoparticles offer some specific advantages over liposomes. For instance, they help to increase the stability of drugs/proteins and possess useful controlled release properties.
Pages: [1] 2 3 4 5 6 7
TIGRESS comment`s:
Wow, who wrote an unusually published!
03.12.2009
The Definition Of InsomniaThe Definition Of InsomniaAuthor: Mason HintonInsomnia is the sensation of daytime fatigue and impaired performance caused by insufficient sleep. In general, people with insomnia experience an inability to sleep despite being tired, a light, fitful sleep that leaves them fatigued upon awakening, or waking up too early. Under debate is the question of whether insomnia is always a symptom of some other physical or psychological condition or whether in some cases it is a primary disorder of its own.Common symptoms of insomnia include:• feeling tired during the day• having frequent headaches• irritability• lack of concentration• you wake up feeling tired and not refreshed• sleeping better away from home• taking longer than 30 or 40 minutes to fall asleep• waking repeatedly during the night• waking far too early and being unable to fall back asleep• being able to sleep only with the aid of sleeping pills or alcoholInsomniacs often complain of being unable to close their eyes or rest their minds for any period of time. |
Math Tutor Nyc the Most Sensible Decision for Your Child’s FutureMath Tutor Nyc the Most Sensible Decision for Your Child’s FutureAuthor: Hugh GoldsmithMath can be a cause for a lot of kid stress and trauma. Children sometimes cry when they have to do their Math homework and it is a complex subject to understand. Math is not only important in every field of life but it is the most important aspect since by not knowing handy math you could easily be fooled. Students sometimes are so afraid of the subject that they develop a phobia towards it. This would ruin their chances of being upgraded to the next class. |